3iy8: Difference between revisions
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==Leishmania tarentolae Mitonchondrial Ribosome small subunit== | ==Leishmania tarentolae Mitonchondrial Ribosome small subunit== | ||
< | <SX load='3iy8' size='340' side='right' viewer='molstar' caption='[[3iy8]], [[Resolution|resolution]] 14.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3iy8]] is a | <table><tr><td colspan='2'>[[3iy8]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Leishmania_tarentolae Leishmania tarentolae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IY8 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14.1Å</td></tr> | ||
<table> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iy8 OCA], [https://pdbe.org/3iy8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iy8 RCSB], [https://www.ebi.ac.uk/pdbsum/3iy8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iy8 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RS5_ECOLI RS5_ECOLI] With S4 and S12 plays an important role in translational accuracy. Many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations).<ref>PMID:15652481</ref> Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<ref>PMID:15652481</ref> The physical location of this protein suggests it may also play a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp.<ref>PMID:15652481</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/3iy8_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/3iy8_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iy8 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| Line 33: | Line 29: | ||
*[[Ribosomal protein S8|Ribosomal protein S8]] | *[[Ribosomal protein S8|Ribosomal protein S8]] | ||
*[[Ribosomal protein S9|Ribosomal protein S9]] | *[[Ribosomal protein S9|Ribosomal protein S9]] | ||
*[[Ribosome 3D structures|Ribosome 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</ | </SX> | ||
[[Category: Escherichia coli | [[Category: Escherichia coli K-12]] | ||
[[Category: Large Structures]] | |||
[[Category: | |||
[[Category: Leishmania tarentolae]] | [[Category: Leishmania tarentolae]] | ||
[[Category: | [[Category: Agrawal RK]] | ||
[[Category: | [[Category: Booth TM]] | ||
[[Category: | [[Category: Maslov DA]] | ||
[[Category: | [[Category: Sharma MR]] | ||
[[Category: | [[Category: Simpson L]] | ||
Latest revision as of 13:07, 21 February 2024
Leishmania tarentolae Mitonchondrial Ribosome small subunitLeishmania tarentolae Mitonchondrial Ribosome small subunit
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