3iy8: Difference between revisions

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[[Image:3iy8.png|left|200px]]


{{STRUCTURE_3iy8|  PDB=3iy8  |  SCENE=  }}
==Leishmania tarentolae Mitonchondrial Ribosome small subunit==
 
<SX load='3iy8' size='340' side='right' viewer='molstar' caption='[[3iy8]], [[Resolution|resolution]] 14.10&Aring;' scene=''>
===Leishmania tarentolae Mitonchondrial Ribosome small subunit===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3iy8]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Leishmania_tarentolae Leishmania tarentolae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3IY8 FirstGlance]. <br>
{{ABSTRACT_PUBMED_19497863}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14.1&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3iy8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3iy8 OCA], [https://pdbe.org/3iy8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3iy8 RCSB], [https://www.ebi.ac.uk/pdbsum/3iy8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3iy8 ProSAT]</span></td></tr>
==About this Structure==
</table>
[[3iy8]] is a 11 chain structure of [[Ribosomal protein S11]], [[Ribosomal protein S12]], [[Ribosomal protein S15]], [[Ribosomal protein S16]], [[Ribosomal protein S17]], [[Ribosomal protein S18]], [[Ribosomal protein S5]], [[Ribosomal protein S6]], [[Ribosomal protein S8]] and [[Ribosomal protein S9]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Leishmania_tarentolae Leishmania tarentolae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IY8 OCA].  
== Function ==
[https://www.uniprot.org/uniprot/RS5_ECOLI RS5_ECOLI] With S4 and S12 plays an important role in translational accuracy. Many suppressors of streptomycin-dependent mutants of protein S12 are found in this protein, some but not all of which decrease translational accuracy (ram, ribosomal ambiguity mutations).<ref>PMID:15652481</ref>  Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.<ref>PMID:15652481</ref>  The physical location of this protein suggests it may also play a role in mRNA unwinding by the ribosome, possibly by forming part of a processivity clamp.<ref>PMID:15652481</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/3iy8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3iy8 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
Line 17: Line 27:
*[[Ribosomal protein S17|Ribosomal protein S17]]
*[[Ribosomal protein S17|Ribosomal protein S17]]
*[[Ribosomal protein S18|Ribosomal protein S18]]
*[[Ribosomal protein S18|Ribosomal protein S18]]
*[[Ribosomal protein S5|Ribosomal protein S5]]
*[[Ribosomal protein S6|Ribosomal protein S6]]
*[[Ribosomal protein S8|Ribosomal protein S8]]
*[[Ribosomal protein S8|Ribosomal protein S8]]
*[[Ribosomal protein S9|Ribosomal protein S9]]
*[[Ribosomal protein S9|Ribosomal protein S9]]
 
*[[Ribosome 3D structures|Ribosome 3D structures]]
==Reference==
== References ==
<ref group="xtra">PMID:019497863</ref><references group="xtra"/>
<references/>
[[Category: Escherichia coli]]
__TOC__
[[Category: Leishmania tarentolae]]
</SX>
[[Category: Agrawal, R K.]]
[[Category: Escherichia coli K-12]]
[[Category: Booth, T M.]]
[[Category: Large Structures]]
[[Category: Maslov, D A.]]
[[Category: Sharma, M R.]]
[[Category: Simpson, L.]]
[[Category: Antibiotic resistance]]
[[Category: Cryoem]]
[[Category: Endonuclease]]
[[Category: Hydrolase]]
[[Category: Leishmania tarentolae]]
[[Category: Leishmania tarentolae]]
[[Category: Methylation]]
[[Category: Agrawal RK]]
[[Category: Minimal rna.]]
[[Category: Booth TM]]
[[Category: Mitochondrial ribosome]]
[[Category: Maslov DA]]
[[Category: Nuclease]]
[[Category: Sharma MR]]
[[Category: Repressor]]
[[Category: Simpson L]]
[[Category: Ribonucleoprotein]]
[[Category: Ribosomal protein]]
[[Category: Ribosome]]
[[Category: Rna-binding]]
[[Category: Rrna-binding]]
[[Category: Translation regulation]]
[[Category: Trna-binding]]

Latest revision as of 13:07, 21 February 2024

Leishmania tarentolae Mitonchondrial Ribosome small subunitLeishmania tarentolae Mitonchondrial Ribosome small subunit

3iy8, resolution 14.10Å

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