3dc4: Difference between revisions

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[[Image:3dc4.png|left|200px]]


{{STRUCTURE_3dc4|  PDB=3dc4  |  SCENE=  }}
==Crystal structure of the Drosophila kinesin family member NOD in complex with ADP==
 
<StructureSection load='3dc4' size='340' side='right'caption='[[3dc4]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===Crystal structure of the Drosophila kinesin family member NOD in complex with ADP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3dc4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DC4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DC4 FirstGlance]. <br>
{{ABSTRACT_PUBMED_19135893}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dc4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dc4 OCA], [https://pdbe.org/3dc4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dc4 RCSB], [https://www.ebi.ac.uk/pdbsum/3dc4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dc4 ProSAT]</span></td></tr>
[[3dc4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DC4 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/NOD_DROME NOD_DROME] Required for the distributive chromosome segregation of non-exchange chromosomes during meiosis. May be a microtubule motor required to hold distributively "paired" chromosomes at the metaphase plate until anaphase.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dc/3dc4_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dc4 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Kinesin|Kinesin]]
*[[Kinesin 3D Structures|Kinesin 3D Structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:019135893</ref><references group="xtra"/>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Cochran, J C.]]
[[Category: Large Structures]]
[[Category: Kull, F J.]]
[[Category: Cochran JC]]
[[Category: Mulko, N K.]]
[[Category: Kull FJ]]
[[Category: Adp]]
[[Category: Mulko NK]]
[[Category: Atp-binding]]
[[Category: Atpase]]
[[Category: Catalytic domain]]
[[Category: Kinesin]]
[[Category: Microtubule]]
[[Category: Motor protein]]
[[Category: Nucleotide-binding]]
[[Category: Nucleotide-binding protein]]

Latest revision as of 12:40, 21 February 2024

Crystal structure of the Drosophila kinesin family member NOD in complex with ADPCrystal structure of the Drosophila kinesin family member NOD in complex with ADP

Structural highlights

3dc4 is a 1 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NOD_DROME Required for the distributive chromosome segregation of non-exchange chromosomes during meiosis. May be a microtubule motor required to hold distributively "paired" chromosomes at the metaphase plate until anaphase.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3dc4, resolution 1.90Å

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