2feo: Difference between revisions

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{{Seed}}
[[Image:2feo.png|left|200px]]


<!--
==Mutant R188M of The Cytidine Monophosphate Kinase from E. coli complexed with dCMP==
The line below this paragraph, containing "STRUCTURE_2feo", creates the "Structure Box" on the page.
<StructureSection load='2feo' size='340' side='right'caption='[[2feo]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2feo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2FEO FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2feo|  PDB=2feo |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2feo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2feo OCA], [https://pdbe.org/2feo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2feo RCSB], [https://www.ebi.ac.uk/pdbsum/2feo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2feo ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KCY_ECOLI KCY_ECOLI] ATP, dATP, and GTP are equally effective as phosphate donors. CMP and dCMP are the best phosphate acceptors.<ref>PMID:8190075</ref> <ref>PMID:7836281</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fe/2feo_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2feo ConSurf].
<div style="clear:both"></div>


===Mutant R188M of The Cytidine Monophosphate Kinase from E. coli complexed with dCMP===
==See Also==
 
*[[Cytidine monophosphate kinase|Cytidine monophosphate kinase]]
 
== References ==
==About this Structure==
<references/>
2FEO is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FEO OCA].
__TOC__
[[Category: Cytidylate kinase]]
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Alexov, E.]]
[[Category: Large Structures]]
[[Category: Barzu, O.]]
[[Category: Alexov E]]
[[Category: Bertrand, T.]]
[[Category: Barzu O]]
[[Category: Briozzo, P.]]
[[Category: Bertrand T]]
[[Category: Bucurenci, N.]]
[[Category: Briozzo P]]
[[Category: Gilles, A M.]]
[[Category: Bucurenci N]]
[[Category: Munier-Lehmann, H.]]
[[Category: Gilles AM]]
[[Category: Ofiteru, A.]]
[[Category: Munier-Lehmann H]]
[[Category: Tourneux, L.]]
[[Category: Ofiteru A]]
[[Category: Nucleotide monophosphate kinase]]
[[Category: Tourneux L]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:43:19 2009''

Latest revision as of 12:23, 14 February 2024

Mutant R188M of The Cytidine Monophosphate Kinase from E. coli complexed with dCMPMutant R188M of The Cytidine Monophosphate Kinase from E. coli complexed with dCMP

Structural highlights

2feo is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KCY_ECOLI ATP, dATP, and GTP are equally effective as phosphate donors. CMP and dCMP are the best phosphate acceptors.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. ↑ Yamanaka K, Ogura T, Koonin EV, Niki H, Hiraga S. Multicopy suppressors, mssA and mssB, of an smbA mutation of Escherichia coli. Mol Gen Genet. 1994 Apr;243(1):9-16. PMID:8190075
  2. ↑ Fricke J, Neuhard J, Kelln RA, Pedersen S. The cmk gene encoding cytidine monophosphate kinase is located in the rpsA operon and is required for normal replication rate in Escherichia coli. J Bacteriol. 1995 Feb;177(3):517-23. PMID:7836281

2feo, resolution 2.80Å

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