1z3a: Difference between revisions

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-{{Seed}}
-[[Image:1z3a.png|left|200px]]
-<!--
+==Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli==
-The line below this paragraph, containing "STRUCTURE_1z3a", creates the "Structure Box" on the page.
+<StructureSection load='1z3a' size='340' side='right'caption='[[1z3a]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1z3a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z3A FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-{{STRUCTURE_1z3a|  PDB=1z3a  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z3a OCA], [https://pdbe.org/1z3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z3a RCSB], [https://www.ebi.ac.uk/pdbsum/1z3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z3a ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1z3a TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TADA_ECOLI TADA_ECOLI] Deaminates adenosine-34 to inosine in tRNA-Arg2. Mutation in this protein makes E.coli resistant to the toxic proteins encoded by the gef gene family. Essential for cell viability.<ref>PMID:12110595</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/1z3a_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z3a ConSurf].
+<div style="clear:both"></div>
-===Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli===
+==See Also==
+*[[Adenosine deaminase 3D structures|Adenosine deaminase 3D structures]]
+== References ==
-<!--
+<references/>
-The line below this paragraph, {{ABSTRACT_PUBMED_16700551}}, adds the Publication Abstract to the page
+__TOC__
-(as it appears on PubMed at http://www.pubmed.gov), where 16700551 is the PubMed ID number.
+</StructureSection>
--->
-{{ABSTRACT_PUBMED_16700551}}
-==About this Structure==
-Z3A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3A OCA].
-==Reference==
-Structural and kinetic characterization of Escherichia coli TadA, the wobble-specific tRNA deaminase., Kim J, Malashkevich V, Roday S, Lisbin M, Schramm VL, Almo SC, Biochemistry. 2006 May 23;45(20):6407-16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16700551 16700551]
 [[Category: Escherichia coli]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Pdbx_ordinal=, <PDBx:audit_author.]]
+[[Category: Almo SC]]
-[[Category: Dimer]]
+[[Category: Burley SK]]
-[[Category: Hydrolase]]
+[[Category: Kim J]]
-[[Category: Metalloenzyme]]
+[[Category: Lisbin M]]
-[[Category: New york sgx research center for structural genomic]]
+[[Category: Malashkevich V]]
-[[Category: Nysgxrc]]
-[[Category: Protein structure initiative]]
-[[Category: Psi]]
-[[Category: Structural genomic]]
-[[Category: Trna adenosine deaminase]]
-[[Category: Zinc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 20:06:45 2008''