1z3a

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Crystal structure of tRNA adenosine deaminase TadA from Escherichia coliCrystal structure of tRNA adenosine deaminase TadA from Escherichia coli

Structural highlights

1z3a is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.03Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

TADA_ECOLI Deaminates adenosine-34 to inosine in tRNA-Arg2. Mutation in this protein makes E.coli resistant to the toxic proteins encoded by the gef gene family. Essential for cell viability.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Wolf J, Gerber AP, Keller W. tadA, an essential tRNA-specific adenosine deaminase from Escherichia coli. EMBO J. 2002 Jul 15;21(14):3841-51. PMID:12110595 doi:http://dx.doi.org/10.1093/emboj/cdf362

1z3a, resolution 2.03Å

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OCA