1z3a: Difference between revisions

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-[[Image:1z3a.gif|left|200px]]
- {{Structure
+==Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli==
-|PDB= 1z3a |SIZE=350|CAPTION= <scene name='initialview01'>1z3a</scene>, resolution 2.03&Aring;
+<StructureSection load='1z3a' size='340' side='right'caption='[[1z3a]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
+<table><tr><td colspan='2'>[[1z3a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z3A FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
-|GENE= tada ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01285 nucleoside_deaminase]</span>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z3a OCA], [https://pdbe.org/1z3a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z3a RCSB], [https://www.ebi.ac.uk/pdbsum/1z3a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z3a ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1z3a TOPSAN]</span></td></tr>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z3a OCA], [http://www.ebi.ac.uk/pdbsum/1z3a PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1z3a RCSB]</span>
+</table>
-}}
+== Function ==
+[https://www.uniprot.org/uniprot/TADA_ECOLI TADA_ECOLI] Deaminates adenosine-34 to inosine in tRNA-Arg2. Mutation in this protein makes E.coli resistant to the toxic proteins encoded by the gef gene family. Essential for cell viability.<ref>PMID:12110595</ref>
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z3/1z3a_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z3a ConSurf].
+<div style="clear:both"></div>
-'''Crystal structure of tRNA adenosine deaminase TadA from Escherichia coli'''
+==See Also==
+*[[Adenosine deaminase 3D structures|Adenosine deaminase 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-Z3A is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z3A OCA].
+__TOC__
+</StructureSection>
 [[Category: Escherichia coli]]
-[[Category: Single protein]]
+[[Category: Large Structures]]
-[[Category: Almo, S C.]]
+[[Category: Almo SC]]
-[[Category: Burley, S K.]]
+[[Category: Burley SK]]
-[[Category: Kim, J.]]
+[[Category: Kim J]]
-[[Category: Lisbin, M.]]
+[[Category: Lisbin M]]
-[[Category: Malashkevich, V N.]]
+[[Category: Malashkevich V]]
-[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
-[[Category: dimer]]
-[[Category: metalloenzyme]]
-[[Category: new york structural genomix research consortium]]
-[[Category: nysgxrc]]
-[[Category: protein structure initiative]]
-[[Category: psi]]
-[[Category: structural genomic]]
-[[Category: trna adenosine deaminase]]
-[[Category: zinc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:17:16 2008''