1mkj: Difference between revisions

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[[Image:1mkj.png|left|200px]]


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==Human Kinesin Motor Domain With Docked Neck Linker==
The line below this paragraph, containing "STRUCTURE_1mkj", creates the "Structure Box" on the page.
<StructureSection load='1mkj' size='340' side='right'caption='[[1mkj]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1mkj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MKJ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_1mkj|  PDB=1mkj  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mkj OCA], [https://pdbe.org/1mkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mkj RCSB], [https://www.ebi.ac.uk/pdbsum/1mkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mkj ProSAT]</span></td></tr>
 
</table>
===Human Kinesin Motor Domain With Docked Neck Linker===
== Function ==
 
[https://www.uniprot.org/uniprot/KINH_HUMAN KINH_HUMAN] Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity).
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12368902}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/1mkj_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12368902}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[1mkj]] is a 1 chain structure of [[Kinesin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MKJ OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mkj ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Kinesin]]
*[[Kinesin 3D Structures|Kinesin 3D Structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:12368902</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Budny, M J.]]
[[Category: Large Structures]]
[[Category: Cooke, R.]]
[[Category: Budny MJ]]
[[Category: Fletterick, R.]]
[[Category: Cooke R]]
[[Category: Naber, N.]]
[[Category: Fletterick R]]
[[Category: Rice, S.]]
[[Category: Naber N]]
[[Category: Sindelar, C V.]]
[[Category: Rice S]]
[[Category: Atpase]]
[[Category: Sindelar CV]]
[[Category: Microtubule]]
[[Category: Motor protein]]
[[Category: Myosin]]
[[Category: Neck linker]]
[[Category: Relay helix]]
[[Category: Switch ii]]
[[Category: Transport protein]]

Latest revision as of 10:44, 14 February 2024

Human Kinesin Motor Domain With Docked Neck LinkerHuman Kinesin Motor Domain With Docked Neck Linker

Structural highlights

1mkj is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:, ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KINH_HUMAN Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1mkj, resolution 2.70Å

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OCA
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