1mb2: Difference between revisions

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[[Image:1mb2.png|left|200px]]


{{STRUCTURE_1mb2|  PDB=1mb2  |  SCENE=  }}
==Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation==
 
<StructureSection load='1mb2' size='340' side='right'caption='[[1mb2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
===Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1mb2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MB2 FirstGlance]. <br>
{{ABSTRACT_PUBMED_12473451}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TRP:TRYPTOPHAN'>TRP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mb2 OCA], [https://pdbe.org/1mb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mb2 RCSB], [https://www.ebi.ac.uk/pdbsum/1mb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mb2 ProSAT]</span></td></tr>
[[1mb2]] is a 6 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MB2 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYW_GEOSE SYW_GEOSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mb/1mb2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mb2 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:012473451</ref><references group="xtra"/>
[[Category: Geobacillus stearothermophilus]]
[[Category: Geobacillus stearothermophilus]]
[[Category: Tryptophan--tRNA ligase]]
[[Category: Large Structures]]
[[Category: Bricogne, G.]]
[[Category: Bricogne G]]
[[Category: Carter, C W.]]
[[Category: Carter Jr CW]]
[[Category: Hu, M.]]
[[Category: Hu M]]
[[Category: Huang, X.]]
[[Category: Huang X]]
[[Category: Ilyin, V.]]
[[Category: Ilyin V]]
[[Category: Retailleau, P.]]
[[Category: Retailleau P]]
[[Category: Roversi, P.]]
[[Category: Roversi P]]
[[Category: Vachette, P.]]
[[Category: Vachette P]]
[[Category: Vonrhein, C.]]
[[Category: Vonrhein C]]
[[Category: Weinreb, V.]]
[[Category: Weinreb V]]
[[Category: Yin, Y.]]
[[Category: Yin Y]]
[[Category: Amino acid binding site]]
[[Category: Aminoacyl-trna synthetase]]
[[Category: Ligase]]
[[Category: Rossmann fold]]

Latest revision as of 10:42, 14 February 2024

Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open ConformationCrystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Tryptophan in an Open Conformation

Structural highlights

1mb2 is a 6 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SYW_GEOSE

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1mb2, resolution 2.70Å

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA