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[[Image:1krv.png|left|200px]]


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==Galactoside Acetyltransferase in Complex with CoA and PNP-beta-Gal==
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<StructureSection load='1krv' size='340' side='right'caption='[[1krv]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1krv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. The March 2003 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''lac Repressor''  by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2003_3 10.2210/rcsb_pdb/mom_2003_3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KRV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KRV FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=147:1-O-[P-NITROPHENYL]-BETA-D-GALACTOPYRANOSE'>147</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
{{STRUCTURE_1krv| PDB=1krv |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1krv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1krv OCA], [https://pdbe.org/1krv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1krv RCSB], [https://www.ebi.ac.uk/pdbsum/1krv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1krv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THGA_ECOLI THGA_ECOLI] May assist cellular detoxification by acetylating non-metabolizable pyranosides, thereby preventing their reentry into the cell.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/1krv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1krv ConSurf].
<div style="clear:both"></div>


===Galactoside Acetyltransferase in Complex with CoA and PNP-beta-Gal===
==See Also==
 
*[[Galactoside O-acetyltransferase|Galactoside O-acetyltransferase]]
 
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{{ABSTRACT_PUBMED_11937062}}
 
==About this Structure==
1KRV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Additional information on 1KRV is available in a page on [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb39_1.html lac Repressor] at the RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KRV OCA].
 
==Reference==
Structure of the lac operon galactoside acetyltransferase., Wang XG, Olsen LR, Roderick SL, Structure. 2002 Apr;10(4):581-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11937062 11937062]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Galactoside O-acetyltransferase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: Lac Repressor]]
[[Category: Lac Repressor]]
[[Category: Olsen, L R.]]
[[Category: Olsen LR]]
[[Category: Roderick, S L.]]
[[Category: Roderick SL]]
[[Category: Wang, X G.]]
[[Category: Wang X-G]]
[[Category: Left-handed parallel beta helix]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 23 10:50:59 2008''

Latest revision as of 10:27, 14 February 2024

Galactoside Acetyltransferase in Complex with CoA and PNP-beta-GalGalactoside Acetyltransferase in Complex with CoA and PNP-beta-Gal

Structural highlights

1krv is a 3 chain structure with sequence from Escherichia coli. The March 2003 RCSB PDB Molecule of the Month feature on lac Repressor by David S. Goodsell is 10.2210/rcsb_pdb/mom_2003_3. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.8Å
Ligands:,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

THGA_ECOLI May assist cellular detoxification by acetylating non-metabolizable pyranosides, thereby preventing their reentry into the cell.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1krv, resolution 2.80Å

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