1ctf: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
New page: left|200px<br /> <applet load="1ctf" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ctf, resolution 1.7Å" /> '''STRUCTURE OF THE C-T...
 
No edit summary
 
(18 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:1ctf.gif|left|200px]]<br />
<applet load="1ctf" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1ctf, resolution 1.7&Aring;" />
'''STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RIBOSOMAL PROTEIN L7/L12 FROM ESCHERICHIA COLI AT 1.7 ANGSTROMS'''<br />


==Overview==
==STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RIBOSOMAL PROTEIN L7/L12 FROM ESCHERICHIA COLI AT 1.7 ANGSTROMS==
The structure of a C-terminal fragment of the ribosomal protein L7/L12, from Escherichia coli has been refined using crystallographic data to 1.7, A resolution. The R-value is 17.4%. Six residues at the N terminus are too, disordered in the structure to be localized. These residues are probably, part of a hinge in the complete L7/L12 molecule. The possibility that a, 2-fold crystallographic axis is a molecular 2-fold axis is discussed. A, patch of invariant residues on the surface of the dimer is probably, involved in functional interactions with elongation factors.
<StructureSection load='1ctf' size='340' side='right'caption='[[1ctf]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1ctf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CTF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1CTF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ctf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ctf OCA], [https://pdbe.org/1ctf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ctf RCSB], [https://www.ebi.ac.uk/pdbsum/1ctf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ctf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RL7_ECOLI RL7_ECOLI] Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation.[HAMAP-Rule:MF_00368]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ct/1ctf_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ctf ConSurf].
<div style="clear:both"></div>


==About this Structure==
==See Also==
1CTF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with SO4 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1CTF OCA].
*[[Ribosomal protein L7/L12|Ribosomal protein L7/L12]]
 
__TOC__
==Reference==
</StructureSection>
Structure of the C-terminal domain of the ribosomal protein L7/L12 from Escherichia coli at 1.7 A., Leijonmarck M, Liljas A, J Mol Biol. 1987 Jun 5;195(3):555-79. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=3309338 3309338]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Leijonmarck, M.]]
[[Category: Leijonmarck M]]
[[Category: Liljas, A.]]
[[Category: Liljas A]]
[[Category: SO4]]
[[Category: ribosomal protein]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Thu Nov  8 12:38:31 2007''

Latest revision as of 09:45, 7 February 2024

STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RIBOSOMAL PROTEIN L7/L12 FROM ESCHERICHIA COLI AT 1.7 ANGSTROMSSTRUCTURE OF THE C-TERMINAL DOMAIN OF THE RIBOSOMAL PROTEIN L7/L12 FROM ESCHERICHIA COLI AT 1.7 ANGSTROMS

Structural highlights

1ctf is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.7Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

RL7_ECOLI Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation.[HAMAP-Rule:MF_00368]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1ctf, resolution 1.70Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/wiki/index.php?title=1ctf&oldid=4041321"