6xt8: Difference between revisions
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New page: '''Unreleased structure''' The entry 6xt8 is ON HOLD until Paper Publication Authors: Markova, K., Damborsky, J., Marek, M. Description: Crystal structure of haloalkane dehalogenase va... |
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==Crystal structure of haloalkane dehalogenase variant DhaA115 domain-swapped dimer type-2== | |||
<StructureSection load='6xt8' size='340' side='right'caption='[[6xt8]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6xt8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6XT8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6XT8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6xt8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6xt8 OCA], [https://pdbe.org/6xt8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6xt8 RCSB], [https://www.ebi.ac.uk/pdbsum/6xt8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6xt8 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane. | |||
==See Also== | |||
*[[Dehalogenase 3D structures|Dehalogenase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Synthetic construct]] | ||
[[Category: | [[Category: Damborsky J]] | ||
[[Category: Marek M]] | |||
[[Category: Markova K]] | |||
Latest revision as of 16:12, 24 January 2024
Crystal structure of haloalkane dehalogenase variant DhaA115 domain-swapped dimer type-2Crystal structure of haloalkane dehalogenase variant DhaA115 domain-swapped dimer type-2
Structural highlights
FunctionDHAA_RHORH Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane. See Also |
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