6s4l: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-'''Unreleased structure'''
-The entry 6s4l is ON HOLD
+==Structure of human KCTD1==
+<StructureSection load='6s4l' size='340' side='right'caption='[[6s4l]], [[Resolution|resolution]] 2.42&Aring;' scene=''>
-Authors: Pinkas, D.M., Bufton, J.C., Fox, A.E., Pike, A.C.W., Newman, J.A., Krojer, T., Shrestha, L., Burgess-Brown, N.A., von Delft, F., Arrowsmith, C., Edwards, A., Bountra, C., Bullock, A.N.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6s4l]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6S4L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6S4L FirstGlance]. <br>
-Description: Structure of human KCTD1
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-[[Category: Pinkas, D.M]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6s4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6s4l OCA], [https://pdbe.org/6s4l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6s4l RCSB], [https://www.ebi.ac.uk/pdbsum/6s4l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6s4l ProSAT]</span></td></tr>
-[[Category: Pike, A.C.W]]
+</table>
-[[Category: Fox, A.E]]
+== Disease ==
-[[Category: Shrestha, L]]
+[https://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN] Scalp-ear-nipple syndrome. The disease is caused by mutations affecting the gene represented in this entry.
-[[Category: Newman, J.A]]
+== Function ==
-[[Category: Edwards, A]]
+[https://www.uniprot.org/uniprot/KCTD1_HUMAN KCTD1_HUMAN] May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.<ref>PMID:18358072</ref> <ref>PMID:19115315</ref>
-[[Category: Burgess-Brown, N.A]]
+== References ==
-[[Category: Krojer, T]]
+<references/>
-[[Category: Von Delft, F]]
+__TOC__
-[[Category: Bountra, C]]
+</StructureSection>
-[[Category: Bullock, A.N]]
+[[Category: Homo sapiens]]
-[[Category: Arrowsmith, C]]
+[[Category: Large Structures]]
-[[Category: Bufton, J.C]]
+[[Category: Arrowsmith C]]
+[[Category: Bountra C]]
+[[Category: Bufton JC]]
+[[Category: Bullock AN]]
+[[Category: Burgess-Brown NA]]
+[[Category: Edwards A]]
+[[Category: Fox AE]]
+[[Category: Krojer T]]
+[[Category: Newman JA]]
+[[Category: Pike ACW]]
+[[Category: Pinkas DM]]
+[[Category: Shrestha L]]
+[[Category: Von Delft F]]