Transcription factor tau: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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 == Structural highlights ==
-The structure of TFIIIC subunit SCF1 DNA-binding domain contains a winged-helix domain and displays a basic patch which is the possible DNA-binding surface<ref>PMID:23921640</ref>.
+TFIIIC contains 6 subunits which are organized in 2 subcomplexes.  Subcomplex A contains the 131 kDa, 95 kDa and 55kDa subunits while subcomplex B contains 138 kDa, 91 kDa and 60 kDa subunits<ref>PMID:32999288</ref>.  The structure of TFIIIC subunit SCF1 DNA-binding domain contains a <scene name='80/801767/Cv/4'>winged-helix domain</scene> (colored in green) and displays a <scene name='80/801767/Cv/5'>basic patch which is the possible DNA-binding surface</scene> (colored in royalblue)<ref>PMID:23921640</ref>.
 </StructureSection>
-==3D structures of transcription factor tau==
+==3D structures of transcription factor tau or TFIIIC==
 Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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 [[4bjj]] - fyTFIIIC subunits SFC1 + SFC7 dimerization domain - fission yeast<br />
 [[4bji]] - fyTFIIIC subunit SFC1 DNA-binding domain <br />
-[[2yn0]] - yTFIIIC subunit SFC7 histidine phosphatase domain - yeast<br />
+[[2yn0]] - yTFIIIC 55 kDa subunit SFC7 histidine phosphatase domain - yeast<br />
-[[5aem]], [[5aio]] - yTFIIIC subunit SFC4 N-terminal TPR array <br />
+[[5aem]], [[5aio]] - yTFIIIC 131 kDa subunit SFC4 N-terminal TPR array <br />
-[[5aim]] - yTFIIIC subunit SFC3  central EWH domain <br />
+[[5aim]] - yTFIIIC 138 kDa subunit SFC3  central EWH domain <br />
+[[6yj6]] - yTFIIIC 131 kDa + 95 kDa + 55 kDa subunits – Cryo EM <br />
+[[8ffz]] - yTFIIIC 138 kDa + 131 kDa + 95 kDa + 60 kDa + 55kDa subunits + TFIIIA + TFIIIB 70 kDa + DNA – Cryo EM <br />
 == References ==
 <references/>
 [[Category:Topic Page]]