4p5a: Difference between revisions

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-'''Unreleased structure'''
-The entry 4p5a is ON HOLD  until Paper Publication
+==Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br UMP==
+<StructureSection load='4p5a' size='340' side='right'caption='[[4p5a]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4p5a]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_asoensis Streptomyces asoensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P5A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P5A FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5BU:5-BROMO-URIDINE-5-MONOPHOSPHATE'>5BU</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p5a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p5a OCA], [https://pdbe.org/4p5a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p5a RCSB], [https://www.ebi.ac.uk/pdbsum/4p5a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p5a ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/C1IC19_9ACTN C1IC19_9ACTN] Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.[HAMAP-Rule:MF_01408]
-Authors: Li, Y., Chen, W., Li, J., Xia, Z., Deng, Z., Zhou, J.
+==See Also==
+*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
-Description: Crystal structure of a UMP/dUMP methylase PolB from Streptomyces cacaoi bound with 5-Br UMP
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Xia, Z]]
+[[Category: Large Structures]]
-[[Category: Li, J]]
+[[Category: Streptomyces asoensis]]
-[[Category: Li, Y]]
+[[Category: Chen W]]
-[[Category: Chen, W]]
+[[Category: Deng Z]]
-[[Category: Zhou, J]]
+[[Category: Li J]]
-[[Category: Deng, Z]]
+[[Category: Li Y]]
+[[Category: Xia Z]]
+[[Category: Zhou J]]