1vek: Difference between revisions

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==Solution Structure of RSGI RUH-011, a UBA Domain from Arabidopsis cDNA==
==Solution Structure of RSGI RUH-011, a UBA Domain from Arabidopsis cDNA==
<StructureSection load='1vek' size='340' side='right' caption='[[1vek]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='1vek' size='340' side='right'caption='[[1vek]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1vek]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VEK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VEK FirstGlance]. <br>
<table><tr><td colspan='2'>[[1vek]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VEK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VEK FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Arabidopsis thaliana genomic DNA, chromosome 3, TAC clone: K10D20 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vek OCA], [http://pdbe.org/1vek PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1vek RCSB], [http://www.ebi.ac.uk/pdbsum/1vek PDBsum], [http://www.topsan.org/Proteins/RSGI/1vek TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vek OCA], [https://pdbe.org/1vek PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vek RCSB], [https://www.ebi.ac.uk/pdbsum/1vek PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vek ProSAT], [https://www.topsan.org/Proteins/RSGI/1vek TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/UBP14_ARATH UBP14_ARATH]] Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Involved in seed and embryo development.<ref>PMID:11576424</ref> <ref>PMID:11788751</ref>
[https://www.uniprot.org/uniprot/UBP14_ARATH UBP14_ARATH] Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Involved in seed and embryo development.<ref>PMID:11576424</ref> <ref>PMID:11788751</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/1vek_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ve/1vek_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
Line 22: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Arath]]
[[Category: Arabidopsis thaliana]]
[[Category: Abe, T]]
[[Category: Large Structures]]
[[Category: Higuchi, Y]]
[[Category: Abe T]]
[[Category: Hirota, H]]
[[Category: Higuchi Y]]
[[Category: Kigawa, T]]
[[Category: Hirota H]]
[[Category: Koshiba, S]]
[[Category: Kigawa T]]
[[Category: Structural genomic]]
[[Category: Koshiba S]]
[[Category: Saito, K]]
[[Category: Saito K]]
[[Category: Yokoyama, S]]
[[Category: Yokoyama S]]
[[Category: Rsgi]]
[[Category: Three helix bundle]]
[[Category: Uba domain]]
[[Category: Ubiquitin associated domain]]
[[Category: Ubiquitin specific protease 14]]
[[Category: Unknown function]]

Latest revision as of 03:02, 28 December 2023

Solution Structure of RSGI RUH-011, a UBA Domain from Arabidopsis cDNASolution Structure of RSGI RUH-011, a UBA Domain from Arabidopsis cDNA

Structural highlights

1vek is a 1 chain structure with sequence from Arabidopsis thaliana. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

UBP14_ARATH Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Involved in seed and embryo development.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Doelling JH, Yan N, Kurepa J, Walker J, Vierstra RD. The ubiquitin-specific protease UBP14 is essential for early embryo development in Arabidopsis thaliana. Plant J. 2001 Sep;27(5):393-405. PMID:11576424
  2. ↑ Tzafrir I, McElver JA, Liu Cm CM, Yang LJ, Wu JQ, Martinez A, Patton DA, Meinke DW. Diversity of TITAN functions in Arabidopsis seed development. Plant Physiol. 2002 Jan;128(1):38-51. PMID:11788751
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