1vek

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Solution Structure of RSGI RUH-011, a UBA Domain from Arabidopsis cDNASolution Structure of RSGI RUH-011, a UBA Domain from Arabidopsis cDNA

Structural highlights

1vek is a 1 chain structure with sequence from Arabidopsis thaliana. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Solution NMR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

UBP14_ARATH Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Involved in seed and embryo development.[1] [2]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Doelling JH, Yan N, Kurepa J, Walker J, Vierstra RD. The ubiquitin-specific protease UBP14 is essential for early embryo development in Arabidopsis thaliana. Plant J. 2001 Sep;27(5):393-405. PMID:11576424
  2. Tzafrir I, McElver JA, Liu Cm CM, Yang LJ, Wu JQ, Martinez A, Patton DA, Meinke DW. Diversity of TITAN functions in Arabidopsis seed development. Plant Physiol. 2002 Jan;128(1):38-51. PMID:11788751
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