1v5t: Difference between revisions

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-[[Image:1v5t.jpg|left|200px]]<br /><applet load="1v5t" size="350" color="white" frame="true" align="right" spinBox="true"
-caption="1v5t" />
-'''Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein'''<br />
-==About this Structure==
+==Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein==
-V5T is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5T OCA].
+<StructureSection load='1v5t' size='340' side='right'caption='[[1v5t]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1v5t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5T FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5t OCA], [https://pdbe.org/1v5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5t RCSB], [https://www.ebi.ac.uk/pdbsum/1v5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5t ProSAT], [https://www.topsan.org/Proteins/RSGI/1v5t TOPSAN]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/UBCP1_MOUSE UBCP1_MOUSE] Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1. Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly. Has also been reported to stimulate the proteolytic activity of the 26S proteasome.[UniProtKB:Q8WVY7]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5t_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5t ConSurf].
+<div style="clear:both"></div>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Mus musculus]]
-[[Category: Single protein]]
+[[Category: Inoue M]]
-[[Category: Inoue, M.]]
+[[Category: Kigawa T]]
-[[Category: Kigawa, T.]]
+[[Category: Koshiba S]]
-[[Category: Koshiba, S.]]
+[[Category: Tochio N]]
-[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+[[Category: Yokoyama S]]
-[[Category: Tochio, N.]]
+[[Category: Zhao C]]
-[[Category: Yokoyama, S.]]
-[[Category: Zhao, C.]]
-[[Category: hypothetical protein]]
-[[Category: riken structural genomics/proteomics initiative]]
-[[Category: rsgi]]
-[[Category: structural genomics]]
-[[Category: ubiquitin-like fold]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:31:47 2008''