1v5t

Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik ProteinSolution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein

Structural highlights 1v5t is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN Function UBCP1_MOUSE Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1. Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly. Has also been reported to stimulate the proteolytic activity of the 26S proteasome.[UniProtKB:Q8WVY7] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

spinqualitylabelsall models 1v5t Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image