4c45: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

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-{{STRUCTURE_4c45|  PDB=4c45  |  SCENE=  }}
-===Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2)===
-==Function==
+==Crystal structure of human pterin-4-alpha-carbinolamine dehydratase 2 (PCBD2)==
-[[http://www.uniprot.org/uniprot/PHS2_HUMAN PHS2_HUMAN]] Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By similarity).  Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity.
+<StructureSection load='4c45' size='340' side='right'caption='[[4c45]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
+== Structural highlights ==
-==About this Structure==
+<table><tr><td colspan='2'>[[4c45]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C45 FirstGlance]. <br>
-[[4c45]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C45 OCA].
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
-[[Category: 4a-hydroxytetrahydrobiopterin dehydratase]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c45 OCA], [https://pdbe.org/4c45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c45 RCSB], [https://www.ebi.ac.uk/pdbsum/4c45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c45 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PHS2_HUMAN PHS2_HUMAN] Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By similarity).  Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity.
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Large Structures]]
-[[Category: Bountra, C.]]
+[[Category: Arrowsmith CH]]
-[[Category: Burgess-Brown, N.]]
+[[Category: Bountra C]]
-[[Category: Canning, P.]]
+[[Category: Burgess-Brown N]]
-[[Category: Delft, F von.]]
+[[Category: Canning P]]
-[[Category: Edwards, A.]]
+[[Category: Edwards A]]
-[[Category: Kiyani, W.]]
+[[Category: Kiyani W]]
-[[Category: Kopec, J.]]
+[[Category: Kopec J]]
-[[Category: Shrestha, L.]]
+[[Category: Shrestha L]]
-[[Category: Vollmar, M.]]
+[[Category: Vollmar M]]
-[[Category: Yue, W W.]]
+[[Category: Yue WW]]
-[[Category: Lyase]]
+[[Category: Von Delft F]]