4lq2: Difference between revisions

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<StructureSection load='4lq2' size='340' side='right'caption='[[4lq2]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
<StructureSection load='4lq2' size='340' side='right'caption='[[4lq2]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lq2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LQ2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lq2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LQ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LQ2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.694&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gwo|4gwo]], [[4gxa|4gxa]], [[4lon|4lon]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OAS:O-ACETYLSERINE'>OAS</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cysB, STM1713 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=99287 SALTY])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lq2 OCA], [https://pdbe.org/4lq2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lq2 RCSB], [https://www.ebi.ac.uk/pdbsum/4lq2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lq2 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lq2 OCA], [http://pdbe.org/4lq2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lq2 RCSB], [http://www.ebi.ac.uk/pdbsum/4lq2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lq2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CYSB_SALTY CYSB_SALTY]] This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.  
[https://www.uniprot.org/uniprot/CYSB_SALTY CYSB_SALTY] This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.


==See Also==
==See Also==
*[[Transcriptional activator|Transcriptional activator]]
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Salty]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
[[Category: Kumaran, S]]
[[Category: Kumaran S]]
[[Category: Mittal, M]]
[[Category: Mittal M]]
[[Category: Singh, A K]]
[[Category: Singh AK]]
[[Category: Cytoplasmic]]
[[Category: Dna binding]]
[[Category: Gene regulation]]
[[Category: Lttr]]
[[Category: N-acetyl serine binding]]
[[Category: O-acetyl serine]]
[[Category: Rossmann fold]]
[[Category: Transcriptional regulation]]
[[Category: Whth motif/ pbp type ii alpha/beta fold]]

Latest revision as of 17:37, 8 November 2023

Crystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium in complex with effector ligand, O-acetylserineCrystal structure of ligand binding domain of CysB, a LysR member from Salmonella typhimurium in complex with effector ligand, O-acetylserine

Structural highlights

4lq2 is a 1 chain structure with sequence from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.694Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CYSB_SALTY This protein is a positive regulator of gene expression for the cysteine regulon, a system of 10 or more loci involved in the biosynthesis of L-cysteine from inorganic sulfate. The inducer for CysB is N-acetylserine. CysB inhibits its own transcription.

See Also

4lq2, resolution 2.69Å

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