RNA ligase: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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-<StructureSection load='1vgj' size='350' side='right' scene='RNA_ligase/Cv/1' caption='Se-Met RNA ligase (PDB code [[1vgj]])'>
+<StructureSection load='' size='350' side='right' scene='RNA_ligase/Cv/1' caption='Se-Met RNA ligase (PDB code [[1vgj]])'>
-'''RNA ligase''' (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain<ref>PMID:18972386</ref>.   See more details in [[T4 RNA ligase 2 (Rnl2)]] and [[Ligases]].
+'''RNA ligase''' (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain<ref>PMID:18972386</ref>.   '''RNA ligase RtcB''' joins 2',3'-cyclic phosphate and 5'-OH ends<ref>PMID:21757685</ref>.  See more details in [[T4 RNA ligase 2 (Rnl2)]] and [[Ligases]].
 </StructureSection>
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 {{#tree:id=OrganizedByTopic|openlevels=0|
-*RNA ligase
+* RNA ligase
 **[[2c5u]] – T4LigR 1 RNA-binding domain - Enterobacteria phage T4<br />
 **[[1s68]] - T4LigR 2 N-terminal<br />
-**[[1vgj]], [[1vdx]] – PyLigR – ''Pyrococcus horikoshii''<br />
+**[[1vgj]], [[1vdx]] – PhLigR – ''Pyrococcus horikoshii''<br />
+**[[8dcg]] – PhLigR RtcB <br />
 **[[2vug]] – LigR – ''Pyrococcus abyssi''<br />
-**[[5cot]] – NgLigR – ''Naegleria gruberi''<br />
 **[[1xdn]] – LigR 1 editing – ''Trypanosoma brucei''<br />
 **[[1iuh]] – LigR 2’-5’ – ''Thermus thermophilus''<br />
 **[[5cot]] – aLigR – amoeba<br />
+**[[6vt0]], [[6vt1]], [[6vt3]], [[6vt4]], [[6vt5]], [[6vtg]], [[5cov]] – aLigR (mutant) <br />
 * RNA ligase complex
+**[[7p3b]] – hLigR RtcB + GMP + Co - human<br />
 **[[5tt6]] – T4LigR 1 + ATP<br />
 **[[2hvr]], [[2hvs]] – T4LigR 2 + DNA + nucleotide <br />
 **[[2hvq]] - T4LigR 2 + adenosine derivative<br />
 **[[4qak]] - LigR 2’-5’ + AMP – ''Escherichia coli''<br />
-**[[5cou]] – aLigR + ATP<br />
+**[[5cou]], [[6vt6]], [[6vt8]], [[6vt9]], [[6vtb]], [[6vtd]] – aLigR (mutant) + ATP<br />
+**[[6vte]] – aLigR (mutant) + AMP<br />
+**[[6vtf]] – aLigR + pyrophosphate<br />
 **[[5d1o]], [[5d1p]] – LigR ATP-dependent + ATP – ''Methanothermobacter thermautotrophicus''<br />
-**[[4isz]] – PhLigR RtcB + GTP + Mn<br />
+**[[4isz]], [[8dc9]], [[8dca]], [[8dcb]], [[8dcd]], [[8dcf]] – PhLigR RtcB + GTP + ion<br />
 **[[4dwq]], [[4it0]] – PhLigR RtcB + GMP + Mn<br />
 **[[4isj]], [[4dwr]] – PhLigR RtcB + Mn<br />
-**[[5cou]] – NgLigR (mutant) + ATP + Mn<br />
+**[[7lfq]] – PhLigR RtcB + DNA<br />
-**[[5cov]] – NgLigR + Mn<br />
 }}
 == References ==