RNA ligase: Difference between revisions

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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-{{STRUCTURE_1vgj|  PDB=1vgj  | SIZE=300| SCENE=RNA_ligase/Cv/1 |right|CAPTION=Se-Met RNA ligase [[1vgj]] }}
+<StructureSection load='' size='350' side='right' scene='RNA_ligase/Cv/1' caption='Se-Met RNA ligase (PDB code [[1vgj]])'>
+'''RNA ligase''' (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain<ref>PMID:18972386</ref>.   '''RNA ligase RtcB''' joins 2',3'-cyclic phosphate and 5'-OH ends<ref>PMID:21757685</ref>.  See more details in [[T4 RNA ligase 2 (Rnl2)]] and [[Ligases]].
-'''RNA ligase''' (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain.   See more details in [[T4 RNA ligase 2 (Rnl2)]] and [[Ligases]].
+</StructureSection>
+== 3D Structures of RNA ligase ==
+Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+{{#tree:id=OrganizedByTopic|openlevels=0|
+* RNA ligase
+**[[2c5u]] – T4LigR 1 RNA-binding domain - Enterobacteria phage T4<br />
+**[[1s68]] - T4LigR 2 N-terminal<br />
+**[[1vgj]], [[1vdx]] – PhLigR – ''Pyrococcus horikoshii''<br />
+**[[8dcg]] – PhLigR RtcB <br />
+**[[2vug]] – LigR – ''Pyrococcus abyssi''<br />
+**[[1xdn]] – LigR 1 editing – ''Trypanosoma brucei''<br />
+**[[1iuh]] – LigR 2’-5’ – ''Thermus thermophilus''<br />
+**[[5cot]] – aLigR – amoeba<br />
+**[[6vt0]], [[6vt1]], [[6vt3]], [[6vt4]], [[6vt5]], [[6vtg]], [[5cov]] – aLigR (mutant) <br />
-== 3D Structures of RNA ligase ==
+* RNA ligase complex
-Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
+**[[7p3b]] – hLigR RtcB + GMP + Co - human<br />
+**[[5tt6]] – T4LigR 1 + ATP<br />
+**[[2hvr]], [[2hvs]] – T4LigR 2 + DNA + nucleotide <br />
+**[[2hvq]] - T4LigR 2 + adenosine derivative<br />
+**[[4qak]] - LigR 2’-5’ + AMP – ''Escherichia coli''<br />
+**[[5cou]], [[6vt6]], [[6vt8]], [[6vt9]], [[6vtb]], [[6vtd]] – aLigR (mutant) + ATP<br />
+**[[6vte]] – aLigR (mutant) + AMP<br />
+**[[6vtf]] – aLigR + pyrophosphate<br />
+**[[5d1o]], [[5d1p]] – LigR ATP-dependent + ATP – ''Methanothermobacter thermautotrophicus''<br />
+**[[4isz]], [[8dc9]], [[8dca]], [[8dcb]], [[8dcd]], [[8dcf]] – PhLigR RtcB + GTP + ion<br />
+**[[4dwq]], [[4it0]] – PhLigR RtcB + GMP + Mn<br />
+**[[4isj]], [[4dwr]] – PhLigR RtcB + Mn<br />
+**[[7lfq]] – PhLigR RtcB + DNA<br />
-[[2hvr]], [[2hvs]] – T4LigR 2 + DNA + nucleotide – Enterobacteria phage T4<br />
+}}
-[[1s68]] - T4LigR 2 N-terminal<br />
+== References ==
-[[2c5u]] – T4LigR 1 RNA-binding domain<br />
+<references/>
-[[1vgj]], [[1vdx]] – LigR – ''Pyrococcus horikoshii''<br />
-[[2vug]] – LigR – ''Pyrococcus abyssi''<br />
-[[1xdn]] – LigR 1 editing – ''Trypanosoma brucei''<br />
-[[1iuh]] – LigR 2’-5’ – ''Thermus thermophilus''<br />
-[[4qak]] - LigR 2’-5’ – ''Escherichia coli''<br />
 [[Category:Topic Page]]