RNA ligase: Difference between revisions

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{{STRUCTURE_1vgj|  PDB=1vgj  | SIZE=300| SCENE=RNA_ligase/Cv/1 |right|CAPTION=Se-Met RNA ligase [[1vgj]] }}
<StructureSection load='' size='350' side='right' scene='RNA_ligase/Cv/1' caption='Se-Met RNA ligase (PDB code [[1vgj]])'>
'''RNA ligase''' (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain<ref>PMID:18972386</ref>.  '''RNA ligase RtcB''' joins 2',3'-cyclic phosphate and 5'-OH ends<ref>PMID:21757685</ref>.  See more details in [[T4 RNA ligase 2 (Rnl2)]] and [[Ligases]].


'''RNA ligase''' (LigR) is an enzyme which ligates two ribonucleotide chains using ATP and producing AMP, diphosphate and the ligated ribonucleotide chain.  See more details in [[T4 RNA ligase 2 (Rnl2)]] and [[Ligases]].
</StructureSection>
== 3D Structures of RNA ligase == 
 
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
 
* RNA ligase


**[[2c5u]] – T4LigR 1 RNA-binding domain - Enterobacteria phage T4<br />
**[[1s68]] - T4LigR 2 N-terminal<br />
**[[1vgj]], [[1vdx]] – PhLigR – ''Pyrococcus horikoshii''<br />
**[[8dcg]] – PhLigR RtcB <br />
**[[2vug]] – LigR – ''Pyrococcus abyssi''<br />
**[[1xdn]] – LigR 1 editing – ''Trypanosoma brucei''<br />
**[[1iuh]] – LigR 2’-5’ – ''Thermus thermophilus''<br />
**[[5cot]] – aLigR – amoeba<br />
**[[6vt0]], [[6vt1]], [[6vt3]], [[6vt4]], [[6vt5]], [[6vtg]], [[5cov]] – aLigR (mutant) <br />


== 3D Structures of RNA ligase == 
* RNA ligase complex


Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
**[[7p3b]] – hLigR RtcB + GMP + Co - human<br />
**[[5tt6]] – T4LigR 1 + ATP<br />
**[[2hvr]], [[2hvs]] – T4LigR 2 + DNA + nucleotide <br />
**[[2hvq]] - T4LigR 2 + adenosine derivative<br />
**[[4qak]] - LigR 2’-5’ + AMP – ''Escherichia coli''<br />
**[[5cou]], [[6vt6]], [[6vt8]], [[6vt9]], [[6vtb]], [[6vtd]] – aLigR (mutant) + ATP<br />
**[[6vte]] – aLigR (mutant) + AMP<br />
**[[6vtf]] – aLigR + pyrophosphate<br />
**[[5d1o]], [[5d1p]] – LigR ATP-dependent + ATP – ''Methanothermobacter thermautotrophicus''<br />
**[[4isz]], [[8dc9]], [[8dca]], [[8dcb]], [[8dcd]], [[8dcf]] – PhLigR RtcB + GTP + ion<br />
**[[4dwq]], [[4it0]] – PhLigR RtcB + GMP + Mn<br />
**[[4isj]], [[4dwr]] – PhLigR RtcB + Mn<br />
**[[7lfq]] – PhLigR RtcB + DNA<br />


[[2hvr]], [[2hvs]] – T4LigR 2 + DNA + nucleotide – Enterobacteria phage T4<br />
}}
[[1s68]] - T4LigR 2 N-terminal<br />
== References ==
[[2c5u]] – T4LigR 1 RNA-binding domain<br />
<references/>
[[1vgj]], [[1vdx]] – LigR – ''Pyrococcus horikoshii''<br />
[[2vug]] – LigR – ''Pyrococcus abyssi''<br />
[[1xdn]] – LigR 1 editing – ''Trypanosoma brucei''<br />
[[1iuh]] – LigR 2’-5’ – ''Thermus thermophilus''


[[Category:Topic Page]]
[[Category:Topic Page]]

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Michal Harel, Alexander Berchansky, Joel L. Sussman