3vx8: Difference between revisions

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'''Unreleased structure'''


The entry 3vx8 is ON HOLD  until Paper Publication
==Crystal structure of Arabidopsis thaliana Atg7NTD-Atg3 complex==
<StructureSection load='3vx8' size='340' side='right'caption='[[3vx8]], [[Resolution|resolution]] 3.11&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3vx8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VX8 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.11&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vx8 OCA], [https://pdbe.org/3vx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vx8 RCSB], [https://www.ebi.ac.uk/pdbsum/3vx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vx8 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ATG7_ARATH ATG7_ARATH] E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes. Involved in the senescence process.<ref>PMID:12070171</ref>


Authors: Matoba, K., Fujioka, Y, Noda, N.N.
==See Also==
 
*[[Autophagy-related protein 3D structures|Autophagy-related protein 3D structures]]
Description: E1-E2 complex 2
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Fujioka Y]]
[[Category: Matoba K]]
[[Category: Noda NN]]

Latest revision as of 17:13, 18 October 2023

Crystal structure of Arabidopsis thaliana Atg7NTD-Atg3 complexCrystal structure of Arabidopsis thaliana Atg7NTD-Atg3 complex

Structural highlights

3vx8 is a 4 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.11Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ATG7_ARATH E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes. Involved in the senescence process.[1]

See Also

References

  1. ↑ Doelling JH, Walker JM, Friedman EM, Thompson AR, Vierstra RD. The APG8/12-activating enzyme APG7 is required for proper nutrient recycling and senescence in Arabidopsis thaliana. J Biol Chem. 2002 Sep 6;277(36):33105-14. Epub 2002 Jun 17. PMID:12070171 doi:http://dx.doi.org/10.1074/jbc.M204630200

3vx8, resolution 3.11Å

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