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==Cryo-EM structure of IRL1620-bound ETBR-Gi complex== | |||
<StructureSection load='8hbd' size='340' side='right'caption='[[8hbd]], [[Resolution|resolution]] 2.99Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8hbd]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HBD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.99Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hbd OCA], [https://pdbe.org/8hbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hbd RCSB], [https://www.ebi.ac.uk/pdbsum/8hbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hbd ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Duan | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/GBG2_HUMAN GBG2_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity). | ||
[[Category: Jiang | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Duan J]] | |||
[[Category: Ji Y]] | |||
[[Category: Jiang Y]] | |||
[[Category: Xu HE]] | |||
[[Category: Yuan Q]] | |||
Latest revision as of 18:26, 4 October 2023
Cryo-EM structure of IRL1620-bound ETBR-Gi complexCryo-EM structure of IRL1620-bound ETBR-Gi complex
Structural highlights
FunctionGBG2_HUMAN Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity). |
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