Cryo-EM structure of IRL1620-bound ETBR-Gi complexCryo-EM structure of IRL1620-bound ETBR-Gi complex

Structural highlights

8hbd is a 6 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:Electron Microscopy, Resolution 2.99Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

GBG2_HUMAN Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).

8hbd, resolution 2.99Å

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OCA