4l8q: Difference between revisions
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<StructureSection load='4l8q' size='340' side='right'caption='[[4l8q]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='4l8q' size='340' side='right'caption='[[4l8q]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4l8q]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4l8q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_grandiflora Canavalia grandiflora]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L8Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L8Q FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XMM:(2R,3S,4S,5S,6R)-2-(5-BROMO-4-CHLORO-1H-INDOL-3-YLOXY)-TETRAHYDRO-6-(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL'>XMM</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l8q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l8q OCA], [https://pdbe.org/4l8q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l8q RCSB], [https://www.ebi.ac.uk/pdbsum/4l8q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l8q ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/LECA_CANGR LECA_CANGR] Lectin (PubMed:24361256). Induces paw edema in mice (PubMed:22368061). Has a weak vasorelaxant effect on rat aorta (PubMed:24361256). Has anti-inflammatory and anti-nociceptive effects (PubMed:19153712).<ref>PMID:19153712</ref> <ref>PMID:22368061</ref> <ref>PMID:24361256</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Canavalia grandiflora]] | [[Category: Canavalia grandiflora]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Barroso-Neto | [[Category: Barroso-Neto IL]] | ||
[[Category: Bezerra | [[Category: Bezerra MJB]] | ||
[[Category: Cavada | [[Category: Cavada BS]] | ||
[[Category: Delatorre | [[Category: Delatorre P]] | ||
[[Category: Nagano | [[Category: Nagano CS]] | ||
[[Category: Nascimento | [[Category: Nascimento KS]] | ||
[[Category: Osterne | [[Category: Osterne VJS]] | ||
[[Category: Pereira-Junior | [[Category: Pereira-Junior FN]] | ||
[[Category: Rocha | [[Category: Rocha BAM]] | ||
[[Category: Sampaio | [[Category: Sampaio AH]] | ||
[[Category: Simoes | [[Category: Simoes RC]] | ||