3h0x: Difference between revisions

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==Crystal structure of peptide-binding domain of Kar2 protein from Saccharomyces cerevisiae==
The line below this paragraph, containing "STRUCTURE_3h0x", creates the "Structure Box" on the page.
<StructureSection load='3h0x' size='340' side='right'caption='[[3h0x]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3h0x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H0X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H0X FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h0x OCA], [https://pdbe.org/3h0x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h0x RCSB], [https://www.ebi.ac.uk/pdbsum/3h0x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h0x ProSAT], [https://www.topsan.org/Proteins/MCSG/3h0x TOPSAN]</span></td></tr>
{{STRUCTURE_3h0x|  PDB=3h0x  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of peptide-binding domain of Kar2 protein from Saccharomyces cerevisiae===
[https://www.uniprot.org/uniprot/BIP_YEAST BIP_YEAST] Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.<ref>PMID:16002399</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
3H0X is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H0X OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h0/3h0x_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h0x ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Bigelow, L.]]
[[Category: Bigelow L]]
[[Category: Craig, E A.]]
[[Category: Craig EA]]
[[Category: Gu, M.]]
[[Category: Gu M]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak A]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Osipiuk J]]
[[Category: Osipiuk, J.]]
[[Category: Sahi C]]
[[Category: Sahi, C.]]
[[Category: Apc89502 3]]
[[Category: Atp-binding]]
[[Category: Bip]]
[[Category: Chaperone]]
[[Category: Endoplasmic reticulum]]
[[Category: Kar2]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Nucleotide-binding]]
[[Category: Peptide binding]]
[[Category: Phosphoprotein]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Stress response]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 22 11:47:54 2009''

Latest revision as of 10:14, 6 September 2023

Crystal structure of peptide-binding domain of Kar2 protein from Saccharomyces cerevisiaeCrystal structure of peptide-binding domain of Kar2 protein from Saccharomyces cerevisiae

Structural highlights

3h0x is a 1 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.92Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

BIP_YEAST Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Kimura T, Hosoda Y, Sato Y, Kitamura Y, Ikeda T, Horibe T, Kikuchi M. Interactions among yeast protein-disulfide isomerase proteins and endoplasmic reticulum chaperone proteins influence their activities. J Biol Chem. 2005 Sep 9;280(36):31438-41. Epub 2005 Jul 7. PMID:16002399 doi:http://dx.doi.org/10.1074/jbc.M503377200

3h0x, resolution 1.92Å

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