5fwc: Difference between revisions
Jump to navigation
Jump to search
New page: '''Unreleased structure''' The entry 5fwc is ON HOLD Authors: Gallego, P., Navarro, S., Ventura, S., Reverter, D. Description: Human Spectrin SH3 domain D48G, E7A, K60A [[Category: Unr... |
No edit summary |
||
| (4 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
The entry | ==Human Spectrin SH3 domain D48G, E7A, K60A== | ||
<StructureSection load='5fwc' size='340' side='right'caption='[[5fwc]], [[Resolution|resolution]] 1.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5fwc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FWC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwc OCA], [https://pdbe.org/5fwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fwc RCSB], [https://www.ebi.ac.uk/pdbsum/5fwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwc ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] West syndrome. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. | |||
==See Also== | |||
*[[Spectrin 3D structures|Spectrin 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Gallego | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Gallego P]] | ||
[[Category: Ventura | [[Category: Navarro S]] | ||
[[Category: Reverter D]] | |||
[[Category: Ventura S]] | |||
Latest revision as of 16:29, 26 July 2023
Human Spectrin SH3 domain D48G, E7A, K60AHuman Spectrin SH3 domain D48G, E7A, K60A
Structural highlights
DiseaseSPTN1_HUMAN West syndrome. The disease is caused by mutations affecting the gene represented in this entry. FunctionSPTN1_HUMAN Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. See Also |
| ||||||||||||||||||