Ecotin: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

@@ Line 1: / Line 1: @@
-{{STRUCTURE_1id5|  PDB=1id5  | SIZE=400| SCENE= |right|CAPTION=A monomer of the dimeric E. coli ecotin (gold) complex with thrombin heavy chain (pink) and light chain (aqua), protease inhibitor and Ca+2 ion (green) [[1id5]] }}
+<StructureSection load='1id5' size='400' side='right' scene='46/465444/Cv/2' caption='The dimeric E. coli ecotin (yellow) complex with thrombin heavy chain (cyan) and light chain (magenta) and Ca+2 ion (green) [[1id5]]'>
-'''Ecotin''' (ECO) is a serine protease inhibitor found in the periplasm of E. coli.  It is a potent anti and a reversible tight-binding inhibitor of human factor Xa.<ref>PMID:14705961</ref>
+'''Ecotin''' (ECO) is a serine protease inhibitor found in the periplasm of ''E. coli''.  It is a potent anti and a reversible tight-binding inhibitor of human factor Xa.<ref>PMID:14705961</ref>
+<scene name='46/465444/Cv/7'>The dimeric E. coli ecotin</scene> with <scene name='46/465444/Cv/8'>thrombin heavy and light chains</scene>.
+<scene name='46/465444/Cv/9'>Ca+2 ion coordination site</scene> in thrombin heavy chain ([[1id5]]).<ref>PMID:11513582</ref> Water molecules shown as red spheres.
+</StructureSection>
 == 3D Structures of Ecotin ==
@@ Line 24: / Line 28: @@
 **[[1fi8]] - ECO (mutant) + granzyme B<br />
 **[[4iw4]] – ECO + mannan-binding lectin serine protease<br />
+**[[7cbk]] – ECO + elastase<br />
+**[[7pqo]] – ECO (mutant) + MASP-1<br />
+**[[7pqn]] – ECO + MASP-2<br />
 }}
 == References ==
 <references/>
 [[Category:Topic Page]]