Mineralocorticoid receptor: Difference between revisions
No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| (4 intermediate revisions by 2 users not shown) | |||
| Line 4: | Line 4: | ||
== Function == | == Function == | ||
'''Mineralocorticoid receptor''' (MR) in epithelial cells is activated by the mineralocorticoid hormone aldosterone promoting renal sodium retention and potassium excretion. It is[[Nuclear receptors|nuclear receptor]] In non epithelial cells MR is activated by cortisol<ref>PMID:15199296</ref>. MR is exposed to many steroids including cortisol, cortisone and progesterone, however, aldosterone and deoxycorticosterone are its physiological ligands. | '''Mineralocorticoid receptor''' (MR) in epithelial cells is activated by the mineralocorticoid hormone aldosterone promoting renal sodium retention and potassium excretion. It is [[Nuclear receptors|nuclear receptor]]. In non epithelial cells MR is activated by cortisol<ref>PMID:15199296</ref>. MR is exposed to many steroids including cortisol, cortisone and progesterone, however, aldosterone and deoxycorticosterone are its physiological ligands. | ||
See also [[Mineralocorticoids]]; [[Steroid Hormones and their receptors]] and [[Intracellular receptors]] | |||
== Disease == | == Disease == | ||