SARS-CoV-2 protein ORF8: Difference between revisions
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<StructureSection load='7JTL' size='350' | <StructureSection load='7JTL' size='350' side='right' caption='Crystal structure of the SARS-CoV-2 Protein ORF8 (PDB: [7JTL)' scene='84/842074/7jtl_orf8/1'> | ||
== Function == | == Function == | ||
'''Open Reading Frame 8 (ORF8)''' | '''Open Reading Frame 8 (ORF8)''' may play a role in host-virus interaction. Similar to some Bat coronavirus ns8 genes, but is entirely different from SARS ns8a or ns8b<ref>[https://zhanglab.ccmb.med.umich.edu/COVID-19/ Modeling of the SARS-COV-2 Genome]</ref><ref>pmid 32200634</ref>. | ||
<ref>[https://zhanglab.ccmb.med.umich.edu/COVID-19/ Modeling of the SARS-COV-2 Genome]</ref><ref>pmid 32200634</ref> | |||
== Disease == | == Disease == | ||
ORF8 contributes to the virulence of SARS-CoV-2 in COVID-19<ref>PMID: 33361333</ref>. | ORF8 contributes to the virulence of SARS-CoV-2 in COVID-19<ref>PMID: 33361333</ref>. | ||
== Relevance == | == Relevance == | ||
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== See also == | == See also == | ||
[[Coronavirus_Disease 2019 (COVID-19)]] | [[Coronavirus_Disease 2019 (COVID-19)]]<br> | ||
[[SARS-CoV-2_virus_proteins]]<br> | |||
[[COVID-19 AlphaFold2 Models]] | |||
__NOTOC__ | __NOTOC__ | ||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||