Corticosteroids: Difference between revisions
No edit summary |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 2: | Line 2: | ||
Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, [[glucocorticoids]] and [[mineralocorticoids]], are involved in a wide range of physiological processes. | Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, [[glucocorticoids]] and [[mineralocorticoids]], are involved in a wide range of physiological processes. | ||
Prednisone and its derivatives have some mineralocorticoid action in addition to the glucocorticoid | <scene name='89/896210/Cv/1'>Prednisone</scene> and its derivatives have some mineralocorticoid action in addition to the glucocorticoid effect. | ||
<scene name='89/895670/Cv/2'>Cortisol</scene> (hydrocortisone) is a corticosteroid with both glucocorticoid and mineralocorticoid activity and effects. | |||
<scene name='89/895670/Cv/3'>Dexamethasone</scene> is a glucocorticoid medication. It is the most potent glucocorticoid and it has not mineralocorticoid potency. <scene name='89/895670/Cv/4'>Human glucocorticoid receptor ligand-binding domain bound to dexamethasone</scene> ([[1m2z]]). | |||
*[[Glucocorticoids]] | *[[Glucocorticoids]] | ||
*[[Mineralocorticoids]] | *[[Mineralocorticoids]] | ||
*[[Pentaerythritol tetranitrate reductase]] active site contains the cofactor <scene name='49/490063/Cv/5'>FMN</scene> and the <scene name='49/490063/Cv/6'>substrate steroid prednisone</scene><ref>PMID:11428899</ref>. Water molecules are shown as red spheres. <scene name='49/490063/Cv/7'>Whole active site</scene>. | *[[Pentaerythritol tetranitrate reductase]] active site contains the cofactor <scene name='49/490063/Cv/5'>FMN</scene> and the <scene name='49/490063/Cv/6'>substrate steroid prednisone</scene><ref>PMID:11428899</ref>. Water molecules are shown as red spheres. <scene name='49/490063/Cv/7'>Whole active site</scene>. | ||
*[[Corticosteroid-binding globulin]] | |||
</StructureSection> | </StructureSection> | ||
See also: | |||
*[[Steroid Hormones and their receptors]] | |||
== References == | == References == | ||
<references/> | <references/> | ||