Adapter molecule crk: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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 == Function ==
-'''Adapter molecule crk''' (Crk) ('''C'''T10 '''R'''egulatior of '''K'''inase) or '''p38''' is a proto-oncogene which participates in the Reelin signaling cascade.  Crk binds to several tyrosine-phosphorylated proteins.<ref>PMID:12086608</ref>
+'''Adapter molecule crk''' (Crk) ('''C'''T10 '''R'''egulatior of '''K'''inase) or '''p38''' is a proto-oncogene which participates in the Reelin signaling cascade.  Crk binds to several tyrosine-phosphorylated proteins.<ref>PMID:12086608</ref> See also [[SRC]] and [[Oncogenes & Tumor Suppressor Genes]].
 == Structural highlights ==
-Crk domains include several N-terminal SH2 and C-terminal SH3 domains. <scene name='57/573988/Cv/2'>Mouse Crk N terminal SH3 domain complex with proline-rich peptide</scene> ([[1cka]]) is shown.
+Crk domains include several N-terminal SH2 and C-terminal SH3 domains. <scene name='57/573988/Cv/4'>Mouse Crk N terminal SH3 domain complex with proline-rich peptide</scene> ([[1cka]])<ref>PMID:7735837</ref> is shown.
+==3D structures of adapter molecule crk==
+[[Adapter molecule crk 3D structures]]
 </StructureSection>
-==3D structures of adpter molecule crk==
-[[1m30]], [[1m3a]], [[1m3b]], [[1m3c]] – mCrk N terminal SH3 (mutant) – mouse - NMR<br />
-[[2ggr]] – mCrk C terminal SH3 - NMR<br />
-[[2l3p]], [[2l3q]], [[2l3s]] – Crk residues 220-297 – chicken – NMR<br />
-[[1cka]], [[1ckb]] – mCrk N terminal SH3 + proline-rich peptide<br />
-[[1b07]] – mCrk N terminal SH3 + SH3 peptoid inhibitor<br />
-[[1ju5]] – hCrk SH2 + phosphopeptide + Abl SH3 - human<br />
 == References ==
 <references/>
 [[Category:Topic Page]]