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<StructureSection load='1joi' size='450' side='right' caption='Structure of azurin containing Cu+2 ion (PDB code [[1joi]]).' scene='59/593967/Cv/1'>
<StructureSection load='1joi' size='350' side='right' caption='Structure of azurin containing Cu+2 ion (PDB code [[1joi]]).' scene='59/593967/Cv/1'>


== Function ==
== Function ==


'''Azurin''' (AZ) is a blue copper protein.  AZ mediates electron transfer and contains type I copper center.
'''Azurin''' (AZ) is a blue copper protein.  AZ mediates electron transfer and contains type I copper center.<br />
For details see [[Intramolecular Electron Transfer in Azurin]].


== Relevance ==
== Relevance ==
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== Structural highlights ==
== Structural highlights ==


AZ active Cu binding site is shown here. <ref>PMID:8109977</ref>
<scene name='59/593967/Cv/3'>AZ active Cu binding site is shown here</scene>. <ref>PMID:8109977</ref>
</StructureSection>
==3D structures of cAMP-dependent protein kinase==
 
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
 
*Azurin
 
**[[1e65]] – PaAZ – ''Pseudomonas aeruginosa''<br />
 
*Cu+2 containing azurin
 
**[[1azu]], [[1azr]], [[4azu]], [[5azu]], [[1azn]], [[1cc3]], [[1e5y]], [[1e5z]], [[1jze]], [[2ft6]], [[2ft7]], [[2ft8]], [[2fta]], [[3fs9]], [[3fsa]], [[3fsv]], [[3fsw]], [[3fsz]], [[3ft0]]  – PaAZ  <br />
**[[3fq2]], [[4hip]], [[4qkt]]  – PaAZ  (mutant)<br />
**[[1cuo]], [[1uat]] – AZ  – ''Methylomonas''<br />
**[[1joi]] – PfAZ  – ''Pseudomonas fluorrescens''<br />
**[[1nwo]] – PpAZ  – ''Pseudomonas putida''<br />
**[[1nwp]] – PpAZ  + Zn+2<br />
**[[2aza]], [[1azb]], [[1azc]], [[1rkr]] – AxAZ  – ''Achromobacter xylosoxidans''<br />
**[[1dyz]], [[1dz0]], [[2ccw]] – AZ  II – ''Alcaligenes xylosoxidans''<br />
**[[2azu]], [[3azu]], [[1ils]], [[1ilu]], [[2tsa]], [[2tsb]], [[1etj]], [[1ag0]], [[1ezl]], [[1jvo]], [[1gr7]], [[1xb3]], [[1xb6]], [[1xb8]], [[2ghz]], [[2hx7]], [[2oj1]], [[3in0]], [[3fpy]], [[3fq1]],  [3fq2]], [[3fqy]], [[3in2]], [[3jt2]], [[3jtb]], [[3np3]], [[3np4]], [[3oqr]], [[3n2j]], [[3u25]], [[4hhw]], [[4mfh]], [[4ko5]], [[4ko6]], [[4ko7]], [[4ko9]], [[4kob]], [[4koc]], [[4bww]] – PaAZ (mutant)  <br />
**[[1jvl]], [[2idf]] – PaAZ (mutant)  + Ni+2<br />
**[[1uri]], [[1a4a]], [[1a4b]], [[1a4c]] – AdAZ (mutant)  <br />
**[[2h3x]], [[2h47]], [[2iaa]] – AZ  + aromatic amine dehydrogenase – ''Alcaligenes faecalis''<br />
 
*Cu+2 containing lanthanide-modified azurin
 
**[[1bex]], [[1jzi]], [[1jze]], [[1jzf]], [[1jzj]], [[1jzh]] – PaAZ <br />
**[[2i7s]], [[2fnw]], [[2i7o]], [[3ibo]], [[4hhg]], [[4k9j]] – PaAZ (mutant)  <br />
 
*Cu+1 containing azurin
 
**[[1jzg]] – PaAZ  <br />
**[[1r1c]], [[2gi0]], [[1i53]], [[2hx8]], [[2hx9]], [[2hxa]], [[2xv0]], [[2xv2]], [[2xv3]] – PaAZ (mutant)  <br />
 
*Other metals-containing azurin
 
**[[1aiz]] – AdAZ + Cd+2 – ''Achromobacter denitrificans'' <br />
**[[1nzr]] – PaAZ (mutant) + Ni+2 <br />
**[[1vlx]] – PaAZ + Co+2 <br />
**[[1e67]] – PaAZ + Zn+2<br />
**[[2iwe]] – PaAZ (mutant) + Zn+2<br />
**[[3ay2]] – AZ (mutant) + Zn+2 – ''Neisseria Gonorhoeae''<br />
**[[3uge]] – PaAZ + Ag+1 <br />
**[[4hz1]] – PaAZ + Fe+2<br />
**[[4qlw]] – PaAZ (mutant) + Fe+2<br />
**[[4jkn]] – PaAZ + Hg+2<br />
 
}}
 
 
 
 
 
 
 


==3D structures of azurin==
[[Azurin 3D structures]]


</StructureSection>




Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky