View source for 7c4j


==Cryo-EM structure of the yeast Swi/Snf complex in a nucleosome free state==
<StructureSection load='7c4j' size='340' side='right'caption='[[7c4j]], [[Resolution|resolution]] 2.89&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[7c4j]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C4J FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.89&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c4j OCA], [https://pdbe.org/7c4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c4j RCSB], [https://www.ebi.ac.uk/pdbsum/7c4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c4j ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SWI3_YEAST SWI3_YEAST] Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors.

==See Also==
*[[Actin-related protein 3D structures|Actin-related protein 3D structures]]
*[[Helicase 3D structures|Helicase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Guo ZY]]
[[Category: Wang CC]]
[[Category: Zhan XC]]
[[Category: Zhang XF]]