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Cryo-EM structure of the yeast Swi/Snf complex in a nucleosome free stateCryo-EM structure of the yeast Swi/Snf complex in a nucleosome free state
Structural highlights
FunctionSWI3_YEAST Involved in transcriptional activation. Component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. See Also |
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