View source for 5efa


==Structure of Influenza B Lee PB2 cap-binding domain bound to m7GTP==
<StructureSection load='5efa' size='340' side='right'caption='[[5efa]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5efa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_B_virus_(B/Lee/1940) Influenza B virus (B/Lee/1940)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EFA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MGT:7N-METHYL-8-HYDROGUANOSINE-5-TRIPHOSPHATE'>MGT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5efa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5efa OCA], [https://pdbe.org/5efa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5efa RCSB], [https://www.ebi.ac.uk/pdbsum/5efa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5efa ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PB2_INBLE PB2_INBLE] Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity).

==See Also==
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Ma X]]
[[Category: Shia S]]