5efa

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Structure of Influenza B Lee PB2 cap-binding domain bound to m7GTPStructure of Influenza B Lee PB2 cap-binding domain bound to m7GTP

Structural highlights

5efa is a 1 chain structure with sequence from Influenza B virus (B/Lee/1940). Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PB2_INBLE Involved in transcription initiation and cap-stealing mechanism, in which cellular capped pre-mRNA are used to generate primers for viral transcription. Binds the cap of the target pre-RNA which is subsequently cleaved by PB1. May play a role in genome replication (By similarity).

See Also

5efa, resolution 1.90Å

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OCA