View source for 4yif


==Crystal structure of Rv0880==
<StructureSection load='4yif' size='340' side='right'caption='[[4yif]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4yif]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YIF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YIF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.002&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yif OCA], [https://pdbe.org/4yif PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yif RCSB], [https://www.ebi.ac.uk/pdbsum/4yif PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yif ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Y880_MYCTU Y880_MYCTU] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Rv0880 from the pathogen Mycobacterium tuberculosis is classified as a MarR family protein in the Pfam database. It consists of 143 amino acids and has an isoelectric point of 10.9. Crystals of Rv0880 belonged to space group P1, with unit-cell parameters a = 54.97, b = 69.60, c = 70.32 A, alpha = 103.71, beta = 111.06, gamma = 105.83 degrees . The structure of the MarR family transcription regulator Rv0880 was solved at a resolution of 2.0 A with an R(cryst) and R(free) of 21.2 and 24.9%, respectively. The dimeric structure resembles that of other MarR proteins, with each subunit comprising a winged helix-turn-helix domain connected to an alpha-helical dimerization domain.

Structure of the MarR family protein Rv0880 from Mycobacterium tuberculosis.,Gao YR, Feng N, Chen T, Li de F, Bi LJ Acta Crystallogr F Struct Biol Commun. 2015 Jun;71(Pt 6):741-5. doi:, 10.1107/S2053230X15007281. Epub 2015 May 22. PMID:26057805<ref>PMID:26057805</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 4yif" style="background-color:#fffaf0;"></div>

==See Also==
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Bi LJ]]
[[Category: Feng N]]
[[Category: Gao YR]]
[[Category: Li DF]]