Crystal structure of Rv0880Crystal structure of Rv0880

Structural highlights

4yif is a 6 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.002Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

Y880_MYCTU

Publication Abstract from PubMed

Rv0880 from the pathogen Mycobacterium tuberculosis is classified as a MarR family protein in the Pfam database. It consists of 143 amino acids and has an isoelectric point of 10.9. Crystals of Rv0880 belonged to space group P1, with unit-cell parameters a = 54.97, b = 69.60, c = 70.32 A, alpha = 103.71, beta = 111.06, gamma = 105.83 degrees . The structure of the MarR family transcription regulator Rv0880 was solved at a resolution of 2.0 A with an R(cryst) and R(free) of 21.2 and 24.9%, respectively. The dimeric structure resembles that of other MarR proteins, with each subunit comprising a winged helix-turn-helix domain connected to an alpha-helical dimerization domain.

Structure of the MarR family protein Rv0880 from Mycobacterium tuberculosis.,Gao YR, Feng N, Chen T, Li de F, Bi LJ Acta Crystallogr F Struct Biol Commun. 2015 Jun;71(Pt 6):741-5. doi:, 10.1107/S2053230X15007281. Epub 2015 May 22. PMID:26057805[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

See Also

References

  1. Gao YR, Feng N, Chen T, Li de F, Bi LJ. Structure of the MarR family protein Rv0880 from Mycobacterium tuberculosis. Acta Crystallogr F Struct Biol Commun. 2015 Jun;71(Pt 6):741-5. doi:, 10.1107/S2053230X15007281. Epub 2015 May 22. PMID:26057805 doi:http://dx.doi.org/10.1107/S2053230X15007281

4yif, resolution 2.00Å

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