View source for 4lnp


==The first SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin==
<StructureSection load='4lnp' size='340' side='right'caption='[[4lnp]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4lnp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LNP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LNP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lnp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lnp OCA], [https://pdbe.org/4lnp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lnp RCSB], [https://www.ebi.ac.uk/pdbsum/4lnp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lnp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SRBS1_HUMAN SRBS1_HUMAN] Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).[UniProtKB:Q62417]
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Gong Q]]
[[Category: Li F]]
[[Category: Shi Y]]
[[Category: Wu J]]
[[Category: Zhang Z]]
[[Category: Zhao D]]