The first SH3 domain from CAP/Ponsin in complex with proline rich peptide from VinculinThe first SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin

Structural highlights

4lnp is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.41Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SRBS1_HUMAN Plays a role in tyrosine phosphorylation of CBL by linking CBL to the insulin receptor. Required for insulin-stimulated glucose transport. Involved in formation of actin stress fibers and focal adhesions (By similarity).[UniProtKB:Q62417]

4lnp, resolution 1.41Å

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OCA