View source for 2rv7


==Solution structures of the DNA-binding domains (ZF3-ZF4-ZF5) of immune-related zinc-finger protein ZFAT==
<StructureSection load='2rv7' size='340' side='right'caption='[[2rv7]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2rv7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RV7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RV7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rv7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rv7 OCA], [https://pdbe.org/2rv7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rv7 RCSB], [https://www.ebi.ac.uk/pdbsum/2rv7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rv7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ZFAT_HUMAN ZFAT_HUMAN] May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Kigawa T]]
[[Category: Tochio N]]
[[Category: Umehara T]]
[[Category: Yokoyama S]]