2rv7

Solution structures of the DNA-binding domains (ZF3-ZF4-ZF5) of immune-related zinc-finger protein ZFATSolution structures of the DNA-binding domains (ZF3-ZF4-ZF5) of immune-related zinc-finger protein ZFAT

Structural highlights

2rv7 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

ZFAT_HUMAN May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated (By similarity).

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