View source for 2jp6


==Structural and functional characterization of the recombinant form of the Kv1.3 channel blocker Tc32==
<StructureSection load='2jp6' size='340' side='right'caption='[[2jp6]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2jp6]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JP6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JP6 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jp6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jp6 OCA], [https://pdbe.org/2jp6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jp6 RCSB], [https://www.ebi.ac.uk/pdbsum/2jp6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jp6 ProSAT]</span></td></tr>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/KA181_TITOB KA181_TITOB]] Reversible blocker of both Kv1.3/KCNA3 potassium channels (high affinity) and Shaker B (mammalian Kv1.1 analog) potassium channels (very low affinity).<ref>PMID:12445473</ref>  

==See Also==
*[[Potassium channel toxin 3D structures|Potassium channel toxin 3D structures]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Belluzzi, O]]
[[Category: Pertinhez, T A]]
[[Category: Pignatelli, A]]
[[Category: Sforca, M L]]
[[Category: Spisni, A]]
[[Category: Stehling, E G]]
[[Category: Zanchin, N I]]
[[Category: Toxin]]