View source for 6fvc


==Protein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of Engrailed homeodomain mutants==
<StructureSection load='6fvc' size='340' side='right'caption='[[6fvc]], [[NMR_Ensembles_of_Models | 3 NMR models]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6fvc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6FVC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6FVC FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6fvc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6fvc OCA], [http://pdbe.org/6fvc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6fvc RCSB], [http://www.ebi.ac.uk/pdbsum/6fvc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6fvc ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/HMEN_DROME HMEN_DROME]] This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation. 
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</StructureSection>
[[Category: Large Structures]]
[[Category: Jansen, S]]
[[Category: Kozelka, J]]
[[Category: Srb, P]]
[[Category: Trosanova, Z]]
[[Category: Zachrdla, M]]
[[Category: Zidek, L]]
[[Category: Dna]]
[[Category: Dna binding protein]]
[[Category: Engrailed homeodomain]]
[[Category: K52e mutation]]