6fvc

Protein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of Engrailed homeodomain mutantsProtein environment affects the water-tryptophan binding mode. Molecular dynamics simulations of Engrailed homeodomain mutants

Structural highlights

6fvc is a 1 chain structure with sequence from Drosophila melanogaster. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HMEN_DROME This protein specifies the body segmentation pattern. It is required for the development of the central nervous system. Transcriptional regulator that represses activated promoters. Wg signaling operates by inactivating the SGG repression of EN autoactivation.

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OCA