View source for 2miu

{{STRUCTURE_2miu|  PDB=2miu  |  SCENE=  }} 
===Structure of FHL2 LIM adaptor and its Interaction with Ski===

==Function==
[[http://www.uniprot.org/uniprot/FHL2_HUMAN FHL2_HUMAN]] May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.<ref>PMID:15692560</ref> <ref>PMID:16652157</ref> <ref>PMID:18853468</ref>  

==About this Structure==
[[2miu]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MIU OCA]. 

==Reference==
<references group="xtra"/><references/>
[[Category: Medrano, E E.]]
[[Category: Sun, Y.]]
[[Category: Tian, X.]]
[[Category: Weiss, M A.]]
[[Category: Yang, Y.]]
[[Category: Fhl2]]
[[Category: Lim domain]]
[[Category: Protein binding]]